This is the third in a series of six articles that will describe the foundation of evidence and thinking that served as catalyst for the development and evolution of the Applied Learning and Evidence Translation (ALET™) Blueprint first described in 2025 White Paper titled “The Education We Deliver Isn't Built for the Change We Expect,”¹ developed by the ALET™ Collaboratory.

ECHO HBV Global was submitted for consideration of the Outstanding Educational Collaboration Award because it was not only designed to address this important global health issue through education in regions with high prevalence of hepatitis B by collaborating with leaders in these regions, but also because the effects of this education may have a significant effect on the prevalence, morbidity and mortality of hepatitis B in affected regions.